17-Hydroxyprogesterone Blood Test (17-OHP)
Pinpoint the hormonal cause of ambiguous genitalia or hypertension.
The 17-Hydroxyprogesterone (17-OHP) blood test measures the level of this steroid hormone, which is produced by the adrenal glands and gonads. It is primarily used to screen for and monitor congenital adrenal hyperplasia (CAH), a group of inherited disorders affecting cortisol production. This test is also valuable in investigating causes of ambiguous genitalia in infants, evaluating precocious puberty, and diagnosing adrenal or gonadal tumours. Additionally, it can help assess causes of hypertension and electrolyte imbalances related to adrenal dysfunction.
Biomarkers
- 17-Hydroxyprogesterone (17-OHP)
Why it matters
Measuring 17-OHP provides critical insight into adrenal and gonadal function. Early detection of CAH allows for timely treatment to prevent salt-wasting crises and other complications. For individuals with symptoms such as ambiguous genitalia, early puberty, or unexplained hypertension, this test can guide diagnosis and management, ensuring appropriate care and improved outcomes.
- 17-Hydroxyprogesterone (17-OHP)
No special preparation required.
For blood tests, we recommend drinking plenty of water beforehand to ensure smooth sample collection. If you are taking any regular medication, continue to do so unless advised otherwise by your doctor.
Important Clinical Information:
This test is a screening tool to monitor and support your overall health. It does not replace your GP or Consultant.
Always discuss your test results, especially any abnormal results, with your GP, who can interpret them in the context of your medical history and overall health.