Androstenedione Blood Test
Pinpoint the hormonal source of excess androgens.
The Androstenedione Blood Test measures the level of androstenedione, a steroid hormone produced by the adrenal glands and the gonads (ovaries and testes). It acts as a precursor to testosterone and oestrogen, making it a key marker in the investigation of androgen excess and adrenal or gonadal function. This test is typically requested for women presenting with symptoms such as acne, hirsutism (excess hair growth), irregular periods, or suspected polycystic ovary syndrome (PCOS), and for men or women being investigated for adrenal disorders or ambiguous hormonal findings. It is also used to monitor response to treatment in conditions where androgen production is abnormal.
Androstenedione is measured using a sensitive immunoassay technique, most commonly chemiluminescent immunoassay (CLIA) or enzyme-linked immunosorbent assay (ELISA), which provides accurate and reproducible quantification of the hormone in a simple blood sample.
Biomarkers Included
Adrenal and Gonadal Hormones
- Androstenedione
Why it matters
Androstenedione sits at the crossroads of adrenal and gonadal hormone production. Elevated levels can indicate conditions such as PCOS, congenital adrenal hyperplasia, or an adrenal or ovarian tumour, while low levels may point to adrenal insufficiency or gonadal failure. Measuring androstenedione alongside other hormones helps your doctor identify the source of androgen excess, distinguish between adrenal and ovarian causes, and guide appropriate treatment. For anyone experiencing unexplained hormonal symptoms, this test provides a vital piece of the diagnostic picture.
Adrenal and Gonadal Hormones
- Androstenedione
No special preparation required.
For blood tests, we recommend drinking plenty of water beforehand to ensure smooth sample collection. If you are taking any regular medication, continue to do so unless advised otherwise by your doctor.
Important Clinical Information:
This test is a screening tool to monitor and support your overall health. It does not replace your GP or Consultant.
Always discuss your test results, especially any abnormal results, with your GP, who can interpret them in the context of your medical history and overall health.