Full Body MOT Health Check Plus Cancer & Genotype

The Full Body MOT Plus Cancer and Genotype is our most complete health screening package, bringing together a comprehensive all-round health check, a broad panel of cancer markers, and a full haemoglobin genotype analysis. In a single appointment it assesses your major organ systems, screens a wide range of cancer-related markers, and identifies your sickle cell and thalassaemia status along with any inherited haemoglobin variants. It is our most thorough option for those who want the fullest possible picture of both their current health and their inherited blood makeup.

Physical check and body composition

A detailed set of physical measurements, including height, weight, BMI, blood pressure, pulse rate, body temperature, blood oxygen (SpO2), and a full body composition analysis breaking down fat, muscle, bone, water, and metabolic rate.

Blood group, sugar and genotype

Fasting glucose and HbA1c to check for diabetes and long-term blood sugar control, your ABO and Rh blood group, and a full haemoglobin genotype analysis. This includes your sickle cell and thalassaemia status and a breakdown of your haemoglobin types, showing whether you carry any inherited haemoglobin variants.

Heart (cardiac markers)

Markers reflecting the condition of the heart muscle, including cardiac troponin, creatine kinase (CK and CK-MB), LDH, and HBDH.

Cholesterol (lipids)

A full breakdown of the fats in your blood, including total, HDL, and LDL cholesterol, triglycerides, and the calculated cholesterol ratios.

Kidney function

Markers of how well your kidneys are filtering and clearing waste, including creatinine, urea, uric acid, and eGFR.

Liver function

A detailed assessment of liver health, including the liver enzymes, bilirubin, proteins, bile acids, and other markers of how well the liver is working.

Pancreas

Amylase and lipase, enzymes that reflect the health of the pancreas.

Electrolytes and minerals

Essential salts and minerals reflecting your fluid balance and many body processes, including sodium, potassium, calcium, magnesium, chloride, phosphorus, and bicarbonate.

Inflammation

CRP and high-sensitivity CRP, markers that can indicate inflammation in the body and help assess cardiovascular risk.

Vitamins and iron (micro-elements)

Vitamin D and vitamin B12, both important for energy, nerves, and general health, along with ferritin, the best marker of your iron stores.

Hormones

TSH and free T3 to assess thyroid function, plus testosterone, an important hormone for energy, mood, and sexual health.

Cancer markers

A broad panel of tumour markers relevant to a range of cancers, including markers for bowel, pancreatic, liver, gastric, and blood-related cancers, and sex-specific markers for breast and ovarian cancer in women and prostate and testicular cancer in men. Please read the important note below on how these should be understood.

Blood Count

A complete analysis of your red cells, white cells, and platelets, giving broad insight into anaemia, infection, immune health, and clotting.

Urine analysis

A wide-ranging urine test checking for signs relevant to kidney health, diabetes, infection, and more, including protein, glucose, blood, microalbumin, and the albumin-to-creatinine ratio.

An important note on the cancer markers

This is the most important thing to understand about this package. Tumour markers are screening indicators, not diagnostic tests for cancer, and they must be interpreted with care.

• A normal result does not rule out cancer. Many cancers, especially in their early stages, do not raise these markers, so a normal result should not be taken as an all-clear.
• A raised result does not confirm cancer. These markers are very commonly raised by benign, non-cancerous conditions, so a raised level often has an innocent explanation and does not mean cancer is present.
• Because of this, a raised marker can lead to anxiety and further investigations that turn out to be unnecessary, while a normal marker can give false reassurance.

For these reasons, tumour markers are generally most useful for monitoring people already diagnosed with cancer, rather than for screening people without symptoms. Any raised or abnormal result should always be discussed with your GP, who can consider it in the context of your symptoms, history, and any further tests needed. If you have specific symptoms or concerns about cancer, please speak to your GP directly rather than relying on these markers alone.

A note on your genotype result

The haemoglobin genotype analysis can identify sickle cell and thalassaemia traits and other inherited haemoglobin variants. If you are found to carry a trait, this does not mean you are unwell, but it can be important for family planning, since two carriers can have a child with a more serious condition. Any significant genotype finding is best discussed with your GP, and where relevant, genetic counselling can help explain what it means for you and your family.

Why it matters

Many health conditions develop quietly, with few or no symptoms in their early stages. By checking so many of the body's major systems at once, adding a broad panel of cancer-related markers and a full haemoglobin genotype analysis, this package offers our most complete picture of both your current health and your inherited blood makeup. Used with a clear understanding of what tumour markers can and cannot tell you, and always in discussion with your GP, it can form part of a wider approach to looking after your health.

1. Physical Check & Body Composition
- Weight
- Height
- BMI
- Blood pressure
- Pulse rate
- Body temperature
- Blood oxygen (SpO2)
- Body composition (fat, bone, muscle, water, metabolic rate)

2. Blood Group, Sugar & Genotype
- Fasting glucose
- Haemoglobin A1c (HbA1c)
- Blood group (ABO + Rh)
- Sickle cell status
- Thalassaemia status
- Haemoglobin genotype (HbA0, HbA2, HbF, HbS, HbD, and other variants if present)

3. Cardiac
- Cardiac troponin
- Creatine kinase (CK)
- Creatine kinase-myocardial band (CK-MB)
- Lactate dehydrogenase (LDH)
- Hydroxybutyrate dehydrogenase (HBDH)

4. Cholesterol / Serum Lipids
- Total cholesterol
- HDL cholesterol
- LDL cholesterol
- Triglycerides
- TC/HDL ratio (calculated)
- LDL/HDL ratio (calculated)
- TG/HDL ratio (calculated)

5. Kidney Function
- Creatinine
- Urea
- Uric acid
- eGFR

6. Liver Function
- Albumin
- Total protein
- Globulins
- Alanine transaminase (ALT / SGPT)
- Aspartate aminotransferase (AST / SGOT)
- Alkaline phosphatase (ALP)
- Gamma-glutamyl transferase (GGT)
- Cholinesterase (CHE)
- Total bilirubin (TBIL)
- Direct bilirubin (DBIL)
- Indirect bilirubin (IBIL)
- Total bile acids

7. Pancreas
- Amylase (AMY)
- Lipase (LPS)

8. Electrolytes & Minerals
- Sodium (Na)
- Potassium (K)
- Chloride (Cl)
- Calcium (Ca)
- Magnesium (Mg)
- Phosphorus (P)
- Bicarbonate (tCO2)

9. Cancer Markers
- CA 15-3, breast cancer (women only)
- CA 125, ovarian cancer (women only)
- CA 19-9, pancreatic cancer
- CEA, colorectal cancer
- AFP, liver cancer
- Beta-2 microglobulin (β2-MG), multiple myeloma
- Total PSA and free PSA, prostate cancer (men only)
- Beta-hCG, testicular cancer (men only)
- Pepsinogen I and II (PG1/PG2), gastric cancer

10. Inflammation
- C-reactive protein (CRP / hs-CRP)

11. Micro-elements
- Vitamin D
- Vitamin B12
- Ferritin

12. Hormones
- Thyroid-stimulating hormone (TSH)
- Free triiodothyronine (fT3)
- Testosterone

13. Blood Count

White blood cells
- White blood cell count (WBC)
- Lymphocyte percentage (LYM%)
- Mid-range percentage (MID%)
- Granulocyte percentage (GRAN%)
- Lymphocyte count (LYM#)
- Mid-range count (MID#)
- Granulocyte count (GRAN#)

Red blood cells
- Red blood cell count (RBC)
- Haemoglobin (HGB)
- Haematocrit (HCT)
- Mean corpuscular volume (MCV)
- Mean corpuscular haemoglobin (MCH)
- Mean corpuscular haemoglobin concentration (MCHC)

Platelets
- Platelet count (PLT)
- Mean platelet volume (MPV)
- Platelet distribution width (PDW)
- Platelet large cell ratio (P-LCR)
- Plateletcrit (PCT)

14. Urine Analysis
- pH level
- Specific gravity
- Protein
- Microalbumin
- Glucose
- Ketones
- Blood
- Bilirubin
- Urobilinogen
- Nitrite
- Leukocytes
- Ascorbic acid
- Creatinine
- Calcium
- Albumin-creatinine ratio (uACR)

No special preparation required.

For blood tests, we recommend drinking plenty of water beforehand to ensure smooth sample collection. If you are taking any regular medication, continue to do so unless advised otherwise by your doctor.