Herpes Blood Test (HSV-2 IgM Antibody)
Early detection of recent herpes simplex virus type 2 exposure.
The Herpes Blood Test (HSV-2 IgM Antibody) is a targeted blood test used to detect recent or acute infection with herpes simplex virus type 2 (HSV-2), the virus most commonly associated with genital herpes. This test is suitable for individuals who have been exposed to or are experiencing symptoms suggestive of a new HSV-2 infection, and for clinicians seeking to confirm recent seroconversion. It is not intended for general screening of past or latent infection; IgG antibody testing is more appropriate for that purpose.
The test uses an enzyme-linked immunosorbent assay (ELISA) to detect IgM antibodies, which are typically the first antibodies produced by the immune system following exposure to HSV-2. IgM antibodies generally become detectable within 1 to 2 weeks of infection and may remain present for several weeks to months. A positive result suggests recent or acute infection, while a negative result may indicate no recent exposure, although it does not rule out very early infection before antibody development.
Biomarkers included
Herpes Simplex Virus Type 2 (HSV-2) Serology
- HSV-2 IgM antibody
Why it matters
Early identification of recent HSV-2 infection allows for timely clinical management, appropriate antiviral treatment, and informed discussions about transmission risk. It also supports public health efforts to reduce onward transmission through counselling and partner notification. This test provides a focused, reliable marker of recent immune response to HSV-2, helping patients and clinicians act quickly and appropriately.
Herpes Simplex Virus Type 2 (HSV-2) Serology
- HSV-2 IgM antibody
No special preparation required.
For blood tests, we recommend drinking plenty of water beforehand to ensure smooth sample collection. If you are taking any regular medication, continue to do so unless advised otherwise by your doctor.
Important Clinical Information:
This test is a screening tool to monitor and support your overall health. It does not replace your GP or Consultant.
Always discuss your test results, especially any abnormal results, with your GP, who can interpret them in the context of your medical history and overall health.