Sickle Cell & Genotype Profiles
Compare our sickle cell and haemoglobin genotype tests, with options for blood group testing, red blood cell indices and ferritin (iron storage). Each profile includes haemoglobin variant analysis and beta-thalassaemia screening, with additional assessments available in the Plus profiles.
See what each option includes and choose the profile that best suits your needs. No fasting is required.
Sickle Cell Genotype (AA, AS, SS)
- Turnaround: Same Day
- Sample: Blood
- Biomarkers: 12 analysed
Blood Group & Sickle Cell Genotype (AA, AS, SS)
- Turnaround: Same Day
- Sample: Blood
- Biomarkers: 14 analysed
Sickle Cell Genotype Plus
- Turnaround: Same Day
- Sample: Blood
- Biomarkers: 19 analysed
Blood Group & Sickle Cell Genotype Plus
- Turnaround: Same Day
- Sample: Blood
- Biomarkers: 21 analysed
Key Areas & Packages Comparison
Overview of core screening profiles included across each tier. 2 Common 4 Differing| Screening Area / Profile |
Sickle Cell Genotype (AA, AS, SS)
£105
Standard
|
Blood Group & Sickle Cell Genotype (AA, AS, SS)
£129
Plus Blood Group
|
Sickle Cell Genotype Plus
£145
Plus Thalassaemia
|
Blood Group & Sickle Cell Genotype Plus
£170
Blood Group & Thalassaemia
|
|---|---|---|---|---|
| Genotype and sickle cell status | ||||
| β-thalassaemia screening | ||||
| Blood group: ABO and RhD Tier Difference | — | — | ||
| Red blood cell indices Tier Difference | — | — | ||
| Ferritin: iron storage Tier Difference | — | — | ||
| Assessment for possible α-thalassaemia Tier Difference | — | — |
Biomarkers Analysed Comparison
Total 21 unique markers analysed. 12 Common 9 Differing| Biomarker Parameter |
Sickle Cell Genotype (AA, AS, SS)
£105
Standard
|
Blood Group & Sickle Cell Genotype (AA, AS, SS)
£129
Plus Blood Group
|
Sickle Cell Genotype Plus
£145
Plus Thalassaemia
|
Blood Group & Sickle Cell Genotype Plus
£170
Blood Group & Thalassaemia
|
|---|---|---|---|---|
| General Biomarkers 21 markers | ||||
|
Genotype - AA,AS,AC, etc
|
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Genotype - HbA0
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Genotype - HbA1b
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Genotype - HbA1c
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Genotype - HbA2
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Genotype - HbC
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Genotype - HbD
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Genotype - HbF
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Genotype - HbS
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Genotype - Other variants (if present)
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Genotype - Sickle status
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β - Thalassaemia status (beta)
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Blood Group - ABO
Tier Difference
|
— | — | ||
|
Blood Group - RhD
Tier Difference
|
— | — | ||
|
Ferritin - Iron Storage
Tier Difference
|
— | — | ||
|
Red blood cells - HGB
Tier Difference
|
— | — | ||
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Red blood cells - MCH
Tier Difference
|
— | — | ||
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Red blood cells - MCV
Tier Difference
|
— | — | ||
|
Red blood cells - RBC
Tier Difference
|
— | — | ||
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α - Thalassaemia status (alpha)
Tier Difference
|
— | — | ||
|
δ - Thalassaemia status (delta if present)
Tier Difference
|
— | — | ||
Which Test Do I Need?
Which Sickle Cell & Genotype Profile is right for you?
Standard (£105.00): This tier is ideal for individuals seeking a foundational understanding of their haemoglobin genotype. It includes a full genotype profile (HbA0, HbA2, HbF, HbA1b, HbA1c, HbC, HbS, HbD, and other variants if present), sickle status (e.g. AA, AS, AC), and beta thalassaemia status. Choose this if you primarily want to know your sickle cell trait or disease status and basic beta thalassaemia information, without additional blood group or iron studies.
Plus Thalassaemia (£145.00): Building on the Standard tier, this profile adds red blood cell indices (RBC, HGB, MCV, MCH), ferritin (iron storage), and extended thalassaemia status for alpha, beta, and delta variants. It is suited for those with a family history of thalassaemia, unexplained anaemia, or microcytic blood picture, or for individuals from regions where thalassaemia is more common. The additional red cell and iron markers help distinguish between thalassaemia trait and iron deficiency, providing a more comprehensive haematological assessment.
Plus Blood Group (£129.00): This tier combines the core genotype and beta thalassaemia status of the Standard profile with blood group typing (ABO and RhD). It is an excellent choice for expectant parents, individuals requiring blood group knowledge for medical or transfusion purposes, or anyone curious about their blood type alongside their sickle cell and genotype status. It does not include the extended thalassaemia or red cell indices found in the Plus Thalassaemia tier.
Plus Blood Group & Thalassaemia (£170.00): The most comprehensive option, this tier integrates everything from the previous profiles: full genotype, sickle status, blood group (ABO and RhD), red blood cell indices, ferritin, and alpha, beta, and delta thalassaemia status. It is recommended for individuals who want a complete picture of their haemoglobin genetics, blood group, and iron status, particularly those with a family history of haemoglobinopathies, pre-conception planning, or complex anaemia investigations. This tier provides the deepest diagnostic insight and is ideal when multiple clinical factors need to be assessed together.
Clinical Recommendation
If you are generally healthy and simply wish to know your sickle cell and genotype status, the Standard tier offers excellent value. However, if you have a family history of thalassaemia, anaemia, or are planning a pregnancy, the Plus Thalassaemia or Plus Blood Group & Thalassaemia tiers provide crucial additional information. For blood group knowledge alongside genotype, consider the Plus Blood Group tier. Ultimately, the Plus Blood Group & Thalassaemia tier is the most thorough choice for proactive, comprehensive screening. Always discuss your results with a healthcare professional for personalised advice.
Need personalised clinical guidance?
Our clinical laboratory team in London is available to discuss your testing requirements, pre-test preparation, and help you select the most suitable health profile.