Sickle Cell Genotype Plus
Know your sickle cell status and protect future generations.
The Sickle Cell Genotype Plus test provides a detailed picture of your haemoglobin genetics and red blood cell health. It is designed for anyone who wants to know their carrier status, confirm a suspected haemoglobin variant, or understand the risk of passing an inherited blood disorder to their children. It is particularly valuable for individuals of African, Caribbean, Mediterranean, Middle Eastern, or South Asian heritage, and for couples planning a family.
A simple blood sample is taken in clinic and analysed to identify the exact haemoglobin variants you carry, alongside a full red cell assessment and iron studies to give context to your results.
Haemoglobin Genotype
- Haemoglobin A (HbA0)
- Haemoglobin A2 (HbA2)
- Haemoglobin F (HbF)
- Haemoglobin A1b (HbA1b)
- Haemoglobin A1c (HbA1c)
- Haemoglobin C (HbC)
- Haemoglobin S (HbS)
- Haemoglobin D (HbD)
- Other variants (if present)
- Sickle status
- Thalassaemia status
- Genotype classification (e.g. AA, AS, AC)
Red Blood Cell Profile
- Red blood cell count (RBC)
- Haemoglobin (HGB)
- Mean corpuscular volume (MCV)
- Mean corpuscular haemoglobin (MCH)
Iron Studies
- Ferritin (iron storage)
Thalassaemia Status
- Alpha (α) thalassaemia status
- Beta (β) thalassaemia status
- Gamma (γ) thalassaemia status (if detected)
Why it matters
Knowing your exact haemoglobin genotype allows you to make informed decisions about your health and your family's future. Identifying sickle cell trait or thalassaemia trait early means you can access appropriate monitoring, genetic counselling, and reproductive planning. For couples, understanding both partners' statuses provides clarity on the risk of having a child with a serious inherited blood disorder. The red cell and iron markers add valuable context, helping to distinguish between different causes of anaemia and ensuring any abnormalities are correctly interpreted.
Genotype - HbA0
Genotype - HbA2
Genotype - HbF
Genotype - HbA1b
Genotype - HbA1c
Genotype - HbC
Genotype - HbS
Genotype - HbD
Genotype - Other variants (if present)
Genotype - Sickle status
Genotype - AA,AS,AC, etc
Red blood cells - RBC
Red blood cells - HGB
Red blood cells - MCV
Red blood cells - MCH
Ferritin - Iron Storage
α - Thalassaemia status (alpha)
β - Thalassaemia status (beta)
δ - Thalassaemia status (delta if present)
No special preparation required.
For blood tests, we recommend drinking plenty of water beforehand to ensure smooth sample collection. If you are taking any regular medication, continue to do so unless advised otherwise by your doctor.
Important Clinical Information:
This test is a screening tool to monitor and support your overall health. It does not replace your GP or Consultant.
Always discuss your test results, especially any abnormal results, with your GP, who can interpret them in the context of your medical history and overall health.